SCHEMBL20754591

SCHEMBL20754591

NS(=O)(=O)CC1CCNC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA5 P31644 3/20 0.45
SLC6A1 P30531 2/20 0.45
GABRB2 P47870 2/20 0.45
SLC6A12 P48065 2/20 0.45
SLC6A11 P48066 2/20 0.45
SLC6A13 Q9NSD5 2/20 0.45
GABRA1 P14867 2/20 0.45
GABRR1 P24046 1/20 0.45
GABRA4 P48169 1/20 0.45
APLNR P35414 2/20 0.41
HRH4 Q9H3N8 3/20 0.33
HRH3 Q9Y5N1 3/20 0.33
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
GABRG2 P18507 1/20 0.32
NFKB1 P19838 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4074652 0.98 GABRA5 (0.44) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL20744613 0.88 APLNR (0.52) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL231062 0.86 GABRA5 (0.39) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
Hydrochloric Acid SCHEMBL20744108 0.84 GABRA5 (0.38) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL25040330 0.81
Hydrochloric Acid SCHEMBL31404636 0.79 APLNR (0.31) APLNR
SCHEMBL1702703 0.79 GABRA5 (0.42) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL30804012 0.79 APLNR (0.42) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL6962134 0.78 GABRA5 (0.50) GABRA5SLC6A1GABRB2SLC6A12SLC6A11
SCHEMBL1081079 0.78 GABRA5 (0.45) GABRA5SLC6A1GABRB2SLC6A12SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1934 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106970-A1 DIAGNOSIS AND TREATMENT OF DISEASES COMPLICATED BY SOLUBLE TARGET IN BLOOD CURADEL SURGICAL INNOVATIONS, INC. (US) 2026-05-21 WO claimed
US-20260133198-A1 DIAGNOSIS AND TREATMENT OF DISEASES COMPLICATED BY SOLUBLE TARGET IN BLOOD CURADEL SURGICAL INNOVATIONS, INC. (US) 2026-05-14 US claimed
CN-122011203-A Chimeric antigen receptor with chimeric intracellular signaling domain based on cd3ζ and cd3δ and uses thereof 天宜康医药(上海)有限公司 2026-05-12 CN claimed
EP-4732851-A1 LINKER, ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR Fudan University (CN) 2026-04-29 EP claimed
US-20260102335-A1 IMMUNE CELLS EXPRESSING ENGINEERED ANTIGEN RECEPTORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-04-16 US claimed
EP-4724500-A2 MULTISPECIFIC MOLECULES BINDING TO TCR AND USES THEREOF Marengo Therapeutics, Inc. (US) 2026-04-15 EP claimed
EP-3967329-B1 ENGINEERED IMMUNE CELL TARGETING BCMA AND USE THEREOF GRACELL BIOSCIENCE SHANGHAI CO LTD (CN) 2026-04-01 EP claimed
US-20260069217-A1 APPARATUS AND SYSTEMS FOR EVENT DETECTION USING PROBABILISTIC MEASURES FLINT HILLS SCIENTIFIC, L.L.C. (US) 2026-03-12 US claimed
EP-4704897-A1 COMBINATION THERAPIES USING MOLECULES BINDING TO TCR Marengo Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4706675-A1 CYSTEINE-ENGINEERED CHIMERIC ANTIGEN RECEPTOR Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-03-11 EP claimed
CN-114284518-A Application of PMSA composite membrane obtained based on interface super-assembly in salt gradient energy conversion 复旦大学 2022-04-05 CN claimed
EP-3969483-A1 ULTRASPECIFIC CELL TARGETING USING DE NOVO DESIGNED CO-LOCALIZATION DEPENDENT PROTEIN SWITCHES University of Washington (US) 2022-03-23 EP claimed
EP-3969482-A1 LOCKR-MEDIATED RECRUITMENT OF CAR T CELLS University of Washington (US) 2022-03-23 EP claimed
WO-2022052913-A1 COMPOSITIONS AND METHODS FOR T CELL ENGINEERING GRACELL BIOTECHNOLOGIES (SHANGHAI) CO., LTD. (CN) 2022-03-17 WO claimed
EP-3967329-A1 ENGINEERED IMMUNE CELL TARGETING BCMA AND USE THEREOF Gracell Biotechnologies (Shanghai) Co., Ltd. (CN) 2022-03-16 EP claimed
CN-114181960-A Chimeric antigen receptors and methods of use 美天施生物科技有限公司 2022-03-15 CN claimed
EP-3964238-A1 BCMA-TARGETING ENGINEERED IMMUNE CELL AND USE THEREOF Gracell Biotechnologies (Shanghai) Co., Ltd. (CN) 2022-03-09 EP claimed
CN-114139935-A Method based on OMS and PMS basic data sharing function 国网山东省电力公司日照供电公司 2022-03-04 CN claimed
US-20220049004-A1 ENGINEERED IMMUNE CELLS TARGETING BCMA AND THEIR USES THEREOF GRACELL BIOTECHNOLOGIES (SHANGHAI) CO., LTD. (CN) 2022-02-17 US claimed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133198-A1 DIAGNOSIS AND TREATMENT OF DISEASES COMPLICATED BY SOLUBLE TARGET IN BLOOD KLK3, FUCA2, FAP GABRA5 3435/4885SLC6A1 3495/4885GABRB2 3480/4885
US-20260069217-A1 APPARATUS AND SYSTEMS FOR EVENT DETECTION USING PROBABILISTIC MEASURES STS, NLN, PYGB GABRA5 777/4885SLC6A1 2304/4885GABRB2 1340/4885
US-20260102335-A1 IMMUNE CELLS EXPRESSING ENGINEERED ANTIGEN RECEPTORS CD74, TP53, CAMK2D GABRA5 3561/4885SLC6A1 4764/4885GABRB2 2425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.