Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124189 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL1697190 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL27689216 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL11824600 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL28656061 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL5473941 | 0.82 | PTGS2 (0.52) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL28867820 | 0.79 | HPGD (0.54) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL6567956 | 0.79 | KMT2A (0.58) | SMN1; SMN2GAAMAPK1TSHRPOLB | |
| SCHEMBL2639422 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR | |
| SCHEMBL19028127 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAMAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0426112-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |