Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378371 | 0.88 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6969907 | 0.87 | MEN1 (0.51) | GAASMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL16672740 | 0.77 | TSHR (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7344812 | 0.77 | MEN1 (0.57) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16529634 | 0.76 | ALDH1A1 (0.55) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL7375887 | 0.74 | L3MBTL1 (0.55) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9414267 | 0.73 | AVPR2 (0.40) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL6963217 | 0.73 | KMT2A (0.64) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6965911 | 0.71 | TP53 (0.56) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7654162 | 0.71 | F10 (0.56) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |