Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.56 |
| ▸ | CTSV | O60911 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773829 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1GAASGMS2 | |
| SCHEMBL753131 | 0.80 | MAPT (0.60) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10737968 | 0.79 | MEN1 (0.57) | MEN1KMT2AMAPT | |
| SCHEMBL7378371 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL751204 | 0.78 | MAPT (0.69) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6963299 | 0.77 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2682298 | 0.77 | CTSV (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2CTSV | |
| SCHEMBL26604900 | 0.76 | MEN1 (0.52) | MEN1KMT2AMAPT | |
| SCHEMBL340937 | 0.76 | HTT (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2SGMS2 | |
| SCHEMBL13566609 | 0.75 | SGMS2 (0.69) | MEN1KMT2AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |