Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | EIF4E | P06730 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963299 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2ARAB9AGAALMNA | |
| SCHEMBL7375887 | 0.87 | L3MBTL1 (0.55) | MEN1KMT2ARAB9AGAALMNA | |
| SCHEMBL7820503 | 0.78 | CYP1A2 (0.68) | MEN1KMT2ARAB9AALOX12LMNA | |
| SCHEMBL5216752 | 0.78 | EIF4E (0.56) | MEN1KMT2AGAATSHRCYP3A4 | |
| SCHEMBL9414267 | 0.77 | AVPR2 (0.40) | MEN1KMT2ARAB9AGAALMNA | |
| SCHEMBL2969209 | 0.76 | MEN1 (0.59) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL6702122 | 0.76 | MYC (0.58) | KMT2ARAB9AGAACYP2C9TSHR | |
| SCHEMBL7378371 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2ARAB9AGAALMNA | |
| SCHEMBL406111 | 0.73 | TSHR (0.60) | RAB9AGAATSHRCYP3A4LMNA | |
| SCHEMBL8183777 | 0.72 | HTT (0.64) | MEN1KMT2ARAB9AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |