Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.48 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954047 | 0.85 | ALDH1A1 (0.54) | CNR1CNR2ALDH1A1HTTNPSR1 | |
| SCHEMBL6965063 | 0.84 | KMT2A (0.50) | ALDH1A1HTTTAS2R14NPSR1KMT2A | |
| SCHEMBL6960165 | 0.84 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1HTTTAS2R14 | |
| SCHEMBL6963632 | 0.82 | NPSR1 (0.47) | ALDH1A1NPSR1POLBKMT2AMAPT | |
| SCHEMBL6965348 | 0.80 | SLC6A2 (0.52) | ALDH1A1HTTNPSR1GAAHTR2A | |
| SCHEMBL7342866 | 0.78 | CNR1 (0.60) | CNR1CNR2TSHRALDH1A1MMP3 | |
| Bicarbonate SCHEMBL2492631 | 0.77 | ALDH1A1 (0.65) | CNR1CNR2TSHRALDH1A1MMP3 | |
| SCHEMBL13979925 | 0.76 | ALDH1A1 (0.72) | CNR1CNR2TSHRALDH1A1HTT | |
| SCHEMBL6413655 | 0.74 | MMP3 (0.66) | CNR1CNR2TSHRALDH1A1MMP3 | |
| SCHEMBL13900685 | 0.73 | CNR1 (0.60) | CNR1CNR2TSHRALDH1A1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |