Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954047 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAANPSR1HTT | |
| SCHEMBL6963809 | 0.80 | CNR1 (0.53) | ALDH1A1GAANPSR1HTTHTR2A | |
| SCHEMBL6965063 | 0.80 | KMT2A (0.50) | ALDH1A1GAANPSR1HTT | |
| SCHEMBL6960165 | 0.79 | ALDH1A1 (0.52) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL6963632 | 0.78 | NPSR1 (0.47) | ALDH1A1CA12CA1CA9NPSR1 | |
| SCHEMBL3707659 | 0.77 | BCL2L1 (0.53) | SLC6A2SLC6A4BCL2L1MCL1KCNH2 | |
| SCHEMBL28477897 | 0.69 | KMT2A (0.62) | MCL1ALDH1A1GAANPSR1HTT | |
| Propionic Acid SCHEMBL28042013 | 0.68 | SNCA (0.55) | ALDH1A1GAAHTT | |
| SCHEMBL12309271 | 0.68 | SLC6A2 (0.60) | SLC6A2SLC6A4BCL2L1MCL1KCNH2 | |
| SCHEMBL20021989 | 0.68 | CNR2 (0.62) | SLC6A2SLC6A4ALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |