Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6956807 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL8720453 | 0.87 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| Oxalic Acid SCHEMBL6969816 | 0.85 | RAB9A (0.54) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL8182524 | 0.85 | HRH1 (0.43) | KDM4EALDH1A1KMT2ATSHRSMN1; SMN2 | |
| Oxalic Acid SCHEMBL6970867 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL6967447 | 0.83 | HRH1 (0.48) | ALDH1A1KMT2ATSHRMAPTLTA4H | |
| SCHEMBL6957956 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1KMT2AMAPTLTA4H | |
| Hydrochloric Acid SCHEMBL6965368 | 0.82 | HRH1 (0.47) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL8500525 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL6969835 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934313-B1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-05-14 | — | — | EP | disclosed |
| US-6004983-A | ANALGESICS; ANTIINFLAMMATORY, ANTIARTHRITIC AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0934313-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015549-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |