Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596076 | 0.75 | EGLN1 (0.43) | GLAALDH1A1TDP1 | |
| SCHEMBL536155 | 0.69 | — | — | |
| SCHEMBL402057 | 0.68 | GAA (0.50) | ALDH1A1 | |
| SCHEMBL4024779 | 0.67 | ATM (0.38) | GLAALDH1A1TDP1ATM | |
| SCHEMBL7784530 | 0.66 | ALDH1A1 (0.47) | GLAALDH1A1TDP1ATM | |
| SCHEMBL10876978 | 0.66 | — | — | |
| SCHEMBL8698181 | 0.65 | — | — | |
| SCHEMBL2776894 | 0.65 | — | — | |
| SCHEMBL2776392 | 0.64 | CYP2D6 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL20523440 | 0.63 | LMNA (0.38) | ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817305-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APREPITANT | PIRAMAL ENTPR LTD (IN) | 2016-09-28 | — | — | EP | claimed |
| EP-2817305-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APREPITANT | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | EP | claimed |
| WO-2013124823-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APREPITANT | Piramal Enterprises Limited (IN) | 2013-08-29 | — | — | WO | claimed |
| EP-2817305-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APREPITANT | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124823-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APREPITANT | Piramal Enterprises Limited (IN) | 2013-08-29 | — | — | WO | disclosed |
| EP-1286978-A1 | CYCLOHEXYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-05 | — | — | EP | disclosed |
| EP-1242399-A1 | $g(a)-ARYLETHYLPIPERAZINE DERIVATIVES AS NEUROKININ ANTAGONISTS | UCB S.A. (BE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001087866-A1 | CYCLOHEXYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001046167-A1 | α-ARYLETHYLPIPERAZINE DERIVATIVES AS NEUROKININ ANTAGONISTS | UCB, S.A. (BE) | 2001-06-28 | — | — | WO | disclosed |