Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164804 | 0.78 | APLNR (0.43) | TDP1GAA | |
| SCHEMBL6964169 | 0.75 | GLA (0.32) | ALDH1A1TDP1GLA | |
| SCHEMBL427699 | 0.74 | — | — | |
| SCHEMBL752297 | 0.74 | — | — | |
| SCHEMBL536155 | 0.74 | — | — | |
| SCHEMBL402057 | 0.73 | GAA (0.50) | TSHRALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL8352247 | 0.71 | LDHA (0.50) | EGLN1TSHRCTHALDH1A1TDP1 | |
| SCHEMBL7784530 | 0.71 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1LMNAGAA | |
| SCHEMBL8698181 | 0.70 | — | — | |
| SCHEMBL2776894 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1942472-B | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP. (KR) | 2012-02-15 | — | — | CN | disclosed |
| CN-1798746-B | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP | 2010-09-08 | — | — | CN | disclosed |
| CN-100475816-C | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2009-04-08 | — | — | CN | disclosed |
| CN-1942472-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2007-04-04 | — | — | CN | disclosed |
| CN-1872857-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1872856-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1871239-A | Modulation of beta-catenin/tcf-activated transcription | CHOONGWAE PHARMA CORP (KR) | 2006-11-29 | — | — | CN | disclosed |
| CN-1798746-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-07-05 | — | — | CN | disclosed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | disclosed |