Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633862 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2ATMTSHRKMT2A | |
| SCHEMBL18754039 | 0.83 | GABRA1 (0.42) | GABRA1GABRB2TSHRKMT2AACHE | |
| Ammonia Solution, Strong SCHEMBL28714249 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2ATMTSHRKMT2A | |
| SCHEMBL20249854 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2TSHRKMT2AACHE | |
| Bicarbonate SCHEMBL27556882 | 0.80 | GABRA1 (0.54) | GABRA1GABRB2ATMTSHRKMT2A | |
| SCHEMBL13188023 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2ATMTSHRKMT2A | |
| SCHEMBL8571841 | 0.78 | PDK1 (0.40) | GABRA1GABRB2KMT2AMAPTNPC1 | |
| SCHEMBL4964275 | 0.78 | PLCG1 (0.50) | GABRA1GABRB2TSHRMAPTNPC1 | |
| SCHEMBL12516818 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2ATMTSHRKMT2A | |
| Bicarbonate SCHEMBL5874331 | 0.77 | KMT2A (0.41) | GABRA1GABRB2ATMTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |