Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964185 | 0.95 | GPR119 (0.48) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL7951214 | 0.95 | TGFBR1 (0.44) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6963385 | 0.94 | STS (0.46) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6962633 | 0.94 | MMP13 (0.49) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6968993 | 0.94 | MMP13 (0.50) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6968735 | 0.93 | ITGB3 (0.45) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6976930 | 0.92 | TGFBR1 (0.45) | MMP13TGFBR1 | |
| SCHEMBL6974989 | 0.92 | GPR119 (0.42) | MMP13GPR119MMP1MMP3MMP7 | |
| SCHEMBL6976329 | 0.91 | F2 (0.44) | MMP13GPR119KDM4ETGFBR1LMNA | |
| SCHEMBL6976888 | 0.90 | GPR119 (0.41) | MMP13GPR119MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |