Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964984 | 0.96 | MMP13 (0.39) | MMP13BMP1TP53TGFBR1GPR119 | |
| SCHEMBL6977156 | 0.91 | GPR119 (0.40) | MMP13TGFBR1GPR119MYCMAX | |
| SCHEMBL6964258 | 0.89 | MMP13 (0.50) | MMP13TGFBR1GPR119LMNAMYC | |
| SCHEMBL6976930 | 0.89 | TGFBR1 (0.45) | MMP13TGFBR1MAPT | |
| SCHEMBL6964185 | 0.89 | GPR119 (0.48) | MMP13GPR119MMP1MMP2MMP3 | |
| SCHEMBL7951214 | 0.89 | TGFBR1 (0.44) | MMP13TGFBR1GPR119MMP1MMP2 | |
| SCHEMBL6976329 | 0.88 | F2 (0.44) | MMP13TGFBR1GPR119LMNA | |
| SCHEMBL6963385 | 0.88 | STS (0.46) | MMP13GPR119LMNAMAPTMYC | |
| SCHEMBL6968993 | 0.88 | MMP13 (0.50) | MMP13TGFBR1GPR119MAPTMMP1 | |
| SCHEMBL6962633 | 0.88 | MMP13 (0.49) | MMP13TGFBR1GPR119MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |