Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975141 | 0.82 | ACHE (0.57) | KMT2AKDM4EMEN1MAPTMAPKAPK2 | |
| SCHEMBL7055631 | 0.78 | HSD17B10 (0.57) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL6970367 | 0.78 | L3MBTL1 (0.55) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8436144 | 0.78 | ACHE (0.49) | KDM4EALDH1A1ACHELMNANPSR1 | |
| SCHEMBL6970114 | 0.74 | ACHE (0.60) | KMT2AKDM4EMEN1MAPTMAPKAPK2 | |
| SCHEMBL6976204 | 0.74 | ACHE (0.65) | KMT2AKDM4EMEN1MAPTMAPKAPK2 | |
| SCHEMBL6975573 | 0.73 | ACHE (0.67) | KMT2AKDM4EMEN1MAPTMAPKAPK2 | |
| SCHEMBL6975943 | 0.73 | ACHE (0.64) | KMT2AKDM4EMEN1ALDH1A1ACHE | |
| SCHEMBL6313414 | 0.73 | LMNA (0.72) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL6958811 | 0.73 | ACHE (0.64) | KMT2AKDM4EMEN1MAPTMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |