Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | ACLY | P53396 | 5/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960149 | 0.86 | CCR2 (0.70) | CCR2PPARGACLYNOD1 | |
| SCHEMBL6959902 | 0.86 | PPARG (0.53) | PPARGPPARAPPARDACLY | |
| SCHEMBL3364943 | 0.84 | PPARG (0.49) | PPARGPPARAPPARDACLYFLT1 | |
| SCHEMBL6953098 | 0.82 | CCR2 (0.75) | CCR2PPARGPPARAPPARDACLY | |
| SCHEMBL6964954 | 0.79 | CCR2 (0.56) | CCR2PPARGPPARAPPARDACLY | |
| SCHEMBL6955774 | 0.77 | BCL2 (0.50) | CCR2PPARGPPARAPPARDACLY | |
| SCHEMBL7072404 | 0.74 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3364801 | 0.74 | PPARG (0.46) | PPARGPPARAPPARDACLYNOD1 | |
| SCHEMBL9242590 | 0.72 | RXFP1 (0.52) | CCR2 | |
| SCHEMBL6596517 | 0.72 | CCR2 (0.73) | CCR2ACLYNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001935-B1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | EP | claimed |