Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.53 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.53 |
| ▸ | ACLY | P53396 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955774 | 0.90 | BCL2 (0.50) | PPARGPPARAPPARDACLYMEN1 | |
| SCHEMBL6964749 | 0.86 | CCR2 (0.52) | PPARGPPARAPPARDACLY | |
| SCHEMBL3364943 | 0.82 | PPARG (0.49) | PPARGPPARAPPARDACLYMEN1 | |
| SCHEMBL6959898 | 0.82 | ACLY (0.61) | PPARGPPARAPPARDACLY | |
| SCHEMBL6960770 | 0.78 | NOD2 (0.52) | PPARGPPARAPPARDACLY | |
| SCHEMBL6960149 | 0.75 | CCR2 (0.70) | PPARGACLYALDH1A1KMT2A | |
| SCHEMBL12096838 | 0.74 | PPARG (0.57) | PPARGPPARAPPARDACLYCPT2 | |
| SCHEMBL741459 | 0.74 | ACLY (0.64) | PPARGPPARAPPARDACLYALDH1A1 | |
| SCHEMBL9242590 | 0.73 | RXFP1 (0.52) | MEN1KMT2A | |
| SCHEMBL3364801 | 0.72 | PPARG (0.46) | PPARGPPARAPPARDACLYMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001935-B1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | EP | claimed |