Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 12/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963704 | 0.80 | PPARG (0.49) | ALDH1A1NPSR1PPARGFFAR1MAOA | |
| SCHEMBL6958325 | 0.78 | ADRA2C (0.46) | ALDH1A1SCD | |
| SCHEMBL29764689 | 0.78 | PPARG (0.50) | ALDH1A1NPSR1PPARGFFAR1MAOA | |
| SCHEMBL23578851 | 0.78 | PPARG (0.50) | ALDH1A1NPSR1PPARGFFAR1MAOA | |
| SCHEMBL6964865 | 0.78 | PPARG (0.49) | ALDH1A1NPSR1PPARGFFAR1MAOA | |
| SCHEMBL6964875 | 0.77 | FFAR1 (0.61) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6954013 | 0.76 | MAOA (0.48) | ALDH1A1NPSR1PPARGFFAR1MAOA | |
| SCHEMBL6963261 | 0.75 | PPARG (0.59) | ALDH1A1NPSR1PPARGFFAR1MPC2 | |
| SCHEMBL6964931 | 0.74 | PPARG (0.56) | ALDH1A1PPARGFFAR1MAOACISD1 | |
| SCHEMBL8824957 | 0.74 | SCD (0.39) | ALDH1A1NPSR1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |