Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972397 | 0.91 | KCNH2 (0.34) | IDO1KMT2AMEN1VDRKCNH2 | |
| SCHEMBL7082707 | 0.89 | GRIN1 (0.38) | IDO1ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL6974980 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL6975211 | 0.86 | LMNA (0.37) | ALDH1A1HPGDKMT2AKDM4EMEN1 | |
| SCHEMBL6968750 | 0.85 | PDE4A (0.39) | ALDH1A1HPGDKMT2AKDM4EMEN1 | |
| SCHEMBL6969927 | 0.84 | IDO1 (0.38) | IDO1CSNK2A2CSNK2BHPGDKMT2A | |
| SCHEMBL6971756 | 0.83 | S1PR3 (0.32) | KMT2AMEN1VDRKCNH2 | |
| SCHEMBL7082932 | 0.82 | CSNK2A2 (0.38) | IDO1CSNK2A2CSNK2BALDH1A1HPGD | |
| SCHEMBL7085126 | 0.82 | ALDH1A1 (0.39) | IDO1CSNK2A2CSNK2BALDH1A1HPGD | |
| SCHEMBL7084513 | 0.80 | LMNA (0.39) | CSNK2A2CSNK2BALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |