Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849527 | 0.76 | ALDH1A1 (0.44) | POLBKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9618669 | 0.76 | MAPT (0.44) | EPHX2POLBTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9849537 | 0.76 | KMT2A (0.46) | EPHX2POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7888147 | 0.72 | GAA (0.65) | EPHX2KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10089305 | 0.70 | EPHX1 (1.00) | EPHX1TSHRKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10666079 | 0.69 | CA1 (0.53) | KMT2AMEN1 | |
| SCHEMBL3954720 | 0.69 | NPC1 (0.65) | EPHX1KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3456146 | 0.69 | NPC1 (0.65) | EPHX1KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30073645 | 0.69 | NPC1 (0.65) | EPHX1KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3245449 | 0.69 | CA1 (0.57) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |