Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849537 | 0.83 | KMT2A (0.46) | EPHX2SMYD3POLBKDM1AKMT2A | |
| SCHEMBL9849527 | 0.83 | ALDH1A1 (0.44) | SMYD3POLBKDM1AKMT2AMEN1 | |
| SCHEMBL6965351 | 0.76 | EPHX2 (0.55) | EPHX2POLBKMT2AMEN1LMNA | |
| SCHEMBL9849564 | 0.73 | RAB9A (0.45) | MAPTSMYD3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15916994 | 0.70 | MAPT (0.68) | MAPTEPHX2POLBKMT2AMEN1 | |
| SCHEMBL15916996 | 0.70 | MAPT (0.68) | MAPTEPHX2POLBKMT2AMEN1 | |
| SCHEMBL4432528 | 0.70 | CA1 (0.52) | MAPTPOLBKMT2ACA1CA2 | |
| SCHEMBL29557979 | 0.69 | CA1 (0.56) | MAPTPOLBKMT2ACA1CA2 | |
| SCHEMBL1800130 | 0.69 | CA1 (0.56) | MAPTPOLBKMT2ACA1CA2 | |
| SCHEMBL15934259 | 0.68 | MAPT (0.59) | MAPTEPHX2KDM1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | claimed |
| JP-4352763-A | — | — | None | — | — | JP | disclosed |
| JP-H04352763-A | SULFONYLALKANOIC ACID AMIDE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1992-12-07 | — | — | JP | disclosed |
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | disclosed |