SCHEMBL9849527

SCHEMBL9849527

CC(C(=O)NC1CC1)S(=O)(=O)c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMYD3 Q9H7B4 1/20 0.43
KMT2A Q03164 4/20 0.42
AURKA O14965 1/20 0.42
NTRK1 P04629 1/20 0.42
IGF1R P08069 1/20 0.42
CDK4 P11802 1/20 0.42
EPHA1 P21709 1/20 0.42
CDK2 P24941 1/20 0.42
CDK7 P50613 1/20 0.42
CDK9 P50750 1/20 0.42
CDK3 Q00526 1/20 0.42
CDK6 Q00534 1/20 0.42
CDK5 Q00535 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 1/20 0.41
BTK Q06187 3/20 0.41
P2RX7 Q99572 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849564 0.84 RAB9A (0.45) ALDH1A1SMYD3KMT2ARAB9ACXCR2
SCHEMBL9618669 0.83 MAPT (0.44) SMYD3KMT2APOLBKDM1AMEN1
SCHEMBL9849537 0.83 KMT2A (0.46) ALDH1A1L3MBTL1SMYD3KMT2ANPC1
SCHEMBL6965351 0.76 EPHX2 (0.55) ALDH1A1KMT2ARAB9APOLBKDM4E
SCHEMBL969745 0.75 ALDH1A1 (0.49) ALDH1A1L3MBTL1KMT2ALMNA
SCHEMBL9849374 0.70 SMN1; SMN2 (0.48) KMT2ANPC1RAB9APOLBBTK
SCHEMBL29707953 0.69 HSD11B1 (0.46) ALDH1A1L3MBTL1KMT2A
SCHEMBL8766413 0.69 HSD11B1 (0.46) ALDH1A1L3MBTL1KMT2A
SCHEMBL30484960 0.68 ALDH1A1 (0.64) ALDH1A1L3MBTL1KMT2ANPC1RAB9A
SCHEMBL4030282 0.67 ALDH1A1 (0.87) ALDH1A1L3MBTL1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454459-A2 Sulfonylalkanoic acid amide derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1991-10-30 EP disclosed