SCHEMBL9849537

SCHEMBL9849537

CC(C(=O)NC1CC1)S(=O)(=O)c1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
EPHX2 P34913 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 2/20 0.43
SMYD3 Q9H7B4 1/20 0.43
LMNA P02545 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 1/20 0.41
KDM1A O60341 1/20 0.41
HPGD P15428 1/20 0.41
LIPG Q9Y5X9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618669 0.83 MAPT (0.44) KMT2AMEN1EPHX2SMYD3LMNA
SCHEMBL9849527 0.83 ALDH1A1 (0.44) KMT2AMEN1L3MBTL1ALDH1A1SMYD3
SCHEMBL28144577 0.76 KAT6A (0.44) KMT2AMEN1ALDH1A1LMNANPC1
SCHEMBL6965351 0.76 EPHX2 (0.55) KMT2AMEN1EPHX2ALDH1A1LMNA
SCHEMBL9849564 0.73 RAB9A (0.45) KMT2AMEN1ALDH1A1SMYD3RAB9A
SCHEMBL9849368 0.70 SMN1; SMN2 (0.48) KMT2AMEN1LMNANPC1RAB9A
SCHEMBL30784460 0.69 ALOX5AP (0.46) KMT2AALDH1A1
SCHEMBL9963188 0.69 ALOX5AP (0.46) KMT2AALDH1A1
SCHEMBL12077114 0.67 PSEN1 (0.60) KMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL25464184 0.66 GRM7 (0.73) KMT2AMEN1SMYD3LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454459-A2 Sulfonylalkanoic acid amide derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1991-10-30 EP disclosed