Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965363 | 1.00 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6972432 | 0.78 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6972436 | 0.78 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6990464 | 0.78 | ALDH1A1 (0.52) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL7352245 | 0.76 | MEN1 (0.50) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL7345718 | 0.75 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6965409 | 0.75 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6961949 | 0.74 | MAPT (0.48) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6961951 | 0.74 | MAPT (0.48) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL6962781 | 0.74 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |