Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970953 | 0.85 | RAB9A (0.47) | SMN1; SMN2ACHEBACE1RAB9AMAPT | |
| SCHEMBL7330482 | 0.78 | HPGD (0.54) | SMN1; SMN2RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL8961720 | 0.75 | AVPR2 (0.51) | — | |
| SCHEMBL3044124 | 0.75 | KCNN4 (0.68) | SMN1; SMN2MAPTALDH1A1KCNN4KCNA3 | |
| SCHEMBL7344427 | 0.74 | CA1 (0.54) | SMN1; SMN2MAPTLMNAALDH1A1TSHR | |
| SCHEMBL7344362 | 0.74 | CA1 (0.71) | SMN1; SMN2RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL14509691 | 0.72 | PTPN11 (0.42) | MAPTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL7353072 | 0.72 | TSHR (0.61) | SMN1; SMN2RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7352575 | 0.70 | ALDH1A1 (0.56) | RAB9AMAPTLMNAALDH1A1TSHR | |
| SCHEMBL4251148 | 0.70 | NPC1 (0.58) | SMN1; SMN2RAB9AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |