Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.68 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330482 | 0.86 | HPGD (0.54) | KCNN4KCNA3BCHEP2RX4HPGD | |
| SCHEMBL3037573 | 0.83 | KCNN4 (0.78) | KCNN4KCNA3P2RX4NOTUMHPGD | |
| SCHEMBL7352575 | 0.82 | ALDH1A1 (0.56) | BCHEP2RX4HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL3042508 | 0.81 | KCNN4 (1.00) | KCNN4KCNA3BCHENOTUMHPGD | |
| SCHEMBL6990464 | 0.81 | ALDH1A1 (0.52) | BCHEP2RX4HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL7345718 | 0.80 | ALDH1A1 (0.49) | BCHEP2RX4HPGDL3MBTL1AVPR2 | |
| SCHEMBL8562104 | 0.79 | HPGD (0.58) | HPGDL3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL68111 | 0.77 | KCNN4 (0.68) | KCNN4KCNA3BCHEP2RX4NOTUM | |
| SCHEMBL7349991 | 0.77 | L3MBTL1 (0.46) | KCNN4KCNA3BCHEP2RX4HPGD | |
| SCHEMBL7348630 | 0.77 | L3MBTL1 (0.46) | BCHEP2RX4HPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | 4SC AG (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-1740548-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105752-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | P2RX4, P2RX5, CLIC4 | KCNN4 50/4885KCNA3 52/4885BCHE 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.