Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69658 | 0.94 | MAPT (0.50) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL10786907 | 0.72 | KMT2A (0.56) | MAPTLMNAUSP2GAAAKR1C3 | |
| SCHEMBL995523 | 0.72 | AKR1C3 (0.61) | MAPTALDH1A1LMNAGAAAKR1C3 | |
| Isophthalic Acid SCHEMBL9679148 | 0.71 | DAO (0.62) | MAPTCYP1A2CYP2C9HPGDAKR1C3 | |
| SCHEMBL8848151 | 0.70 | LMNA (0.56) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL28455036 | 0.69 | AKR1C3 (0.58) | MAPTALDH1A1LMNAGAAAKR1C3 | |
| Terephthalic Acid SCHEMBL6660728 | 0.69 | AKR1C3 (0.58) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10497239 | 0.69 | AKR1C3 (0.56) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL11264314 | 0.69 | AKR1C3 (0.56) | MAPTLMNACYP1A2CYP2C9GAA | |
| SCHEMBL11196204 | 0.69 | AKR1C3 (0.61) | MAPTALDH1A1AKR1C3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |