Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69657 | 0.94 | MAPT (0.46) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL11256477 | 0.79 | MAPT (0.50) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL8795307 | 0.71 | MAPT (0.56) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL69684 | 0.66 | NSD2 (0.63) | MAPTALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL9679154 | 0.66 | TOP1 (0.56) | MAPTLMNAUSP2KDM4EGAA | |
| SCHEMBL28168705 | 0.65 | NSD2 (0.61) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8673010 | 0.65 | NSD2 (0.61) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL27267181 | 0.65 | KMT2A (0.83) | MAPTALDH1A1CYP1A2CYP2C19NPC1 | |
| SCHEMBL12857642 | 0.65 | PTGS2 (0.49) | MAPTALDH1A1LMNANPC1KDM4E | |
| SCHEMBL27970386 | 0.65 | ALDH1A1 (0.53) | MAPTALDH1A1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |