Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969363 | 0.84 | ALOX5 (0.47) | ALOX5MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6965763 | 0.80 | L3MBTL1 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6957884 | 0.80 | PTGER4 (0.33) | ALOX5MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17468787 | 0.77 | ALOX5 (0.51) | ALOX5MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9566160 | 0.76 | ALOX5 (0.50) | ALOX5MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9566169 | 0.69 | ALOX5 (0.43) | ALOX5MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL3031292 | 0.69 | — | — | |
| SCHEMBL3100001 | 0.68 | — | — | |
| SCHEMBL13992152 | 0.67 | NPSR1 (0.57) | ALOX5MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6965688 | 0.67 | EPHX2 (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |