Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961499 | 0.86 | MAPT (0.48) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL6965818 | 0.85 | MAPT (0.58) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL27467994 | 0.85 | KMT2A (0.64) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL6960617 | 0.85 | KMT2A (0.53) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL6966945 | 0.84 | MAPT (0.57) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL6962593 | 0.84 | RBP4 (0.61) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL6966427 | 0.83 | KMT2A (0.60) | MAPTALDH1A1MAPK1TSHRKMT2A | |
| SCHEMBL6967897 | 0.83 | KMT2A (0.49) | MAPTALDH1A1MAPK1KMT2AGAA | |
| SCHEMBL7139732 | 0.83 | RBP4 (0.43) | MAPTALDH1A1MAPK1TSHRKMT2A | |
| SCHEMBL8701048 | 0.83 | THRB (0.47) | MAPTLMNAALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |