Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966249 | 0.80 | TAS2R38 (0.48) | GAAMAPTKMT2AMEN1HPGD | |
| SCHEMBL3128742 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2GAAMAPTCYP1A2CYP2C9 | |
| SCHEMBL3996276 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL5108178 | 0.72 | TAS2R38 (0.30) | — | |
| SCHEMBL97108 | 0.72 | HSD17B10 (0.48) | SMN1; SMN2GAAMAPTCYP1A2CYP2C19 | |
| SCHEMBL220757 | 0.72 | — | — | |
| SCHEMBL9725165 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11072074 | 0.69 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6033544 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAMAPTKMT2AMEN1 | |
| SCHEMBL1415961 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |