Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128742 | 0.81 | ALDH1A1 (0.50) | TAS2R38HSD17B10ALDH1A1TP53TYR | |
| SCHEMBL6965986 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1GAAMAPTHPGDL3MBTL1 | |
| SCHEMBL97108 | 0.79 | HSD17B10 (0.48) | HSD17B10ALDH1A1TSHRGAAMAPT | |
| SCHEMBL5108178 | 0.79 | TAS2R38 (0.30) | TAS2R38HSD17B10NAPRT | |
| SCHEMBL6966255 | 0.75 | TGM2 (0.32) | TAS2R38HSD17B10ALDH1A1TP53TYR | |
| SCHEMBL9725165 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1TP53TSHREPHX1MAPT | |
| SCHEMBL1028875 | 0.73 | TDP1 (0.44) | HSD17B10ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL11072074 | 0.72 | SMN1; SMN2 (0.33) | HSD17B10ALDH1A1TP53TSHREPHX1 | |
| SCHEMBL6033544 | 0.72 | SMN1; SMN2 (0.38) | HSD17B10ALDH1A1TP53TSHRGAA | |
| SCHEMBL3996276 | 0.72 | SMN1; SMN2 (0.53) | HSD17B10ALDH1A1TP53TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |