Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967175 | 0.88 | KDM4E (0.38) | MAPTSMN1; SMN2TACR3PDE3BPDE3A | |
| SCHEMBL6963927 | 0.87 | ABCG2 (0.45) | ABCG2MAPTSMN1; SMN2HTR7ALDH1A1 | |
| SCHEMBL6955333 | 0.87 | POLB (0.42) | MAPTSMN1; SMN2TACR3PDE3BPDE3A | |
| SCHEMBL6959295 | 0.87 | MEN1 (0.42) | ABCG2MAPTSMN1; SMN2TACR3PDE3B | |
| SCHEMBL6952935 | 0.85 | MAP4K1 (0.41) | TACR3PDE3BPDE3AHTR7ALDH1A1 | |
| SCHEMBL6966887 | 0.85 | KIT (0.47) | ABCG2MAPTSMN1; SMN2HTR7ALDH1A1 | |
| SCHEMBL6961941 | 0.83 | MAPT (0.42) | ABCG2MAPTSMN1; SMN2TACR3PDE3B | |
| SCHEMBL6966641 | 0.81 | TP53 (0.41) | MAPTSMN1; SMN2HTR7ALDH1A1NPC1 | |
| SCHEMBL6961528 | 0.81 | HTR7 (0.48) | MAPTHTR7ALDH1A1RAB9AHPGD | |
| SCHEMBL6956631 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |