Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959295 | 0.92 | MEN1 (0.42) | HPGDMAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL6966641 | 0.89 | TP53 (0.41) | KDM4EHPGDMAPTNPSR1KMT2A | |
| SCHEMBL6966146 | 0.88 | ABCG2 (0.43) | KDM4EHPGDMAPTPOLBKMT2A | |
| SCHEMBL6956776 | 0.86 | MAP4K1 (0.42) | KDM4EHPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL6956631 | 0.86 | MAPT (0.44) | KDM4EHPGDHSD17B10MAPTPOLB | |
| SCHEMBL6961941 | 0.84 | MAPT (0.42) | KDM4EMAPTNPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL6968659 | 0.83 | MAP4K1 (0.46) | KDM4EHPGDHSD17B10MAPTNPSR1 | |
| SCHEMBL6955333 | 0.81 | POLB (0.42) | KDM4EHSD17B10MAPTPOLBKMT2A | |
| SCHEMBL6963927 | 0.81 | ABCG2 (0.45) | MAPTPOLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6961528 | 0.81 | HTR7 (0.48) | KDM4EHPGDHSD17B10MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |