Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204657 | 0.81 | TGM2 (0.53) | TGM2EGFR | |
| SCHEMBL9725165 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1TP53TSHRHTTNPSR1 | |
| SCHEMBL27477112 | 0.77 | TGM2 (0.49) | TGM2EGFR | |
| SCHEMBL11072074 | 0.76 | SMN1; SMN2 (0.33) | ALDH1A1TP53TSHRHSD17B10 | |
| SCHEMBL6033544 | 0.76 | SMN1; SMN2 (0.38) | ALDH1A1TP53TSHRHSD17B10HTT | |
| SCHEMBL55828 | 0.75 | GAA (0.42) | TAS2R38ALDH1A1TP53TYRTSHR | |
| SCHEMBL97108 | 0.75 | HSD17B10 (0.48) | ALDH1A1TSHRHSD17B10HTTCYP1A2 | |
| SCHEMBL6966249 | 0.75 | TAS2R38 (0.48) | TAS2R38ALDH1A1TP53TYRTSHR | |
| SCHEMBL11465101 | 0.75 | SMN1; SMN2 (0.32) | TGM2TP53TSHRHSD17B10CYP1A2 | |
| SCHEMBL3760045 | 0.73 | PTPN1 (0.46) | TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |