Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086493 | 0.91 | GRIN1 (0.35) | ENPP2PRMT6S1PR3 | |
| SCHEMBL6973648 | 0.88 | KCNH2 (0.34) | PRMT6 | |
| SCHEMBL6961249 | 0.88 | GRIN1 (0.38) | PRMT6GNRHRS1PR3 | |
| SCHEMBL7082084 | 0.88 | ENPP2 (0.35) | ENPP2S1PR3 | |
| SCHEMBL7083358 | 0.87 | KCNK13 (0.32) | ENPP2 | |
| SCHEMBL6960983 | 0.87 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL6974781 | 0.87 | ENPP2 (0.35) | ENPP2S1PR3 | |
| SCHEMBL6973102 | 0.87 | ALOX5 (0.36) | ENPP2GNRHR | |
| SCHEMBL6961221 | 0.87 | — | — | |
| SCHEMBL6960328 | 0.86 | ALDH1A1 (0.37) | PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |