Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 4/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967611 | 0.92 | GRIN1 (0.35) | ALOX5GNRHRNAMPTTP53MAPT | |
| SCHEMBL7081725 | 0.90 | TP53 (0.32) | ALOX5TP53POLBTHRBTLR7 | |
| SCHEMBL7085972 | 0.89 | GRIN1 (0.37) | GNRHRNAMPTPOLBTHRBTLR7 | |
| SCHEMBL6964165 | 0.87 | POLB (0.38) | ALOX5GNRHRTP53MAPTPOLB | |
| SCHEMBL6966552 | 0.87 | ENPP2 (0.31) | GNRHRENPP2 | |
| SCHEMBL7082084 | 0.86 | ENPP2 (0.35) | NAMPTTP53MAPTPOLBENPP2 | |
| SCHEMBL6972096 | 0.85 | LMNA (0.37) | NAMPTTP53POLBTHRB | |
| SCHEMBL6968974 | 0.85 | ALDH1A1 (0.31) | MAPT | |
| SCHEMBL6974781 | 0.85 | ENPP2 (0.35) | NAMPTTP53MAPTPOLBTHRB | |
| SCHEMBL7080069 | 0.84 | S1PR3 (0.37) | GNRHRTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |