Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966395 | 0.86 | FYN (0.43) | MAPTALDH1A1LMNAGFERMAPK1 | |
| SCHEMBL6966641 | 0.84 | TP53 (0.41) | MAPTALDH1A1SMOLMNASMN1; SMN2 | |
| SCHEMBL6955333 | 0.81 | POLB (0.42) | MAPTALDH1A1SMN1; SMN2HTR1AHTR7 | |
| SCHEMBL6967175 | 0.80 | KDM4E (0.38) | MAPTALDH1A1LMNAGFERSMN1; SMN2 | |
| SCHEMBL6956776 | 0.79 | MAP4K1 (0.42) | MAPTALDH1A1LMNAGFERMAPK1 | |
| SCHEMBL6956631 | 0.79 | MAPT (0.44) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6963927 | 0.77 | ABCG2 (0.45) | MAPTALDH1A1LMNAGFERSMN1; SMN2 | |
| SCHEMBL6961941 | 0.77 | MAPT (0.42) | MAPTALDH1A1SMOLMNASMN1; SMN2 | |
| SCHEMBL6961528 | 0.77 | HTR7 (0.48) | MAPTALDH1A1LMNAGFERHTR7 | |
| SCHEMBL6952935 | 0.77 | MAP4K1 (0.41) | ALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |