Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.61 |
| ▸ | CNR2 | P34972 | 10/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657622 | 0.89 | TAS2R14 (0.61) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL6962607 | 0.86 | CNR2 (0.59) | POLBTAS2R14CNR2CNR1MEN1 | |
| SCHEMBL29165194 | 0.85 | TAS2R14 (0.64) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL25984793 | 0.83 | HSD11B1 (0.81) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL29165188 | 0.82 | TAS2R14 (0.62) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL29165498 | 0.82 | TAS2R14 (0.60) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL29165187 | 0.82 | CNR2 (0.60) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL15958717 | 0.81 | KEAP1 (0.59) | POLBTAS2R14CNR2 | |
| SCHEMBL11854252 | 0.80 | CNR2 (0.60) | POLBTAS2R14CNR2CNR1HSD11B1 | |
| SCHEMBL25735705 | 0.79 | TAS2R14 (0.60) | POLBTAS2R14CNR2CNR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |