Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014542 | 0.87 | CNR2 (0.68) | CNR2POLBTAS2R14THRBMEN1 | |
| SCHEMBL6966682 | 0.86 | POLB (0.62) | CNR2POLBTAS2R14MEN1KMT2A | |
| SCHEMBL15958717 | 0.79 | KEAP1 (0.59) | CNR2POLBTAS2R14ALDH1A1 | |
| SCHEMBL22469045 | 0.77 | CNR2 (0.64) | CNR2POLBTAS2R14THRBMEN1 | |
| SCHEMBL22469193 | 0.77 | CNR2 (0.72) | CNR2TAS2R14THRBMEN1ALDH1A1 | |
| SCHEMBL28028814 | 0.76 | HSD11B1 (0.59) | CNR2POLBTAS2R14MEN1KMT2A | |
| SCHEMBL6830704 | 0.76 | CNR2 (0.50) | CNR2POLBTAS2R14MEN1ALDH1A1 | |
| SCHEMBL31287318 | 0.75 | ADAMTS5 (0.60) | CNR2POLBTAS2R14THRBMEN1 | |
| SCHEMBL30657622 | 0.75 | TAS2R14 (0.61) | CNR2POLBTAS2R14MEN1KMT2A | |
| SCHEMBL29165188 | 0.75 | TAS2R14 (0.62) | CNR2POLBTAS2R14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |