Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055631 | 0.80 | HSD17B10 (0.57) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6970367 | 0.80 | L3MBTL1 (0.55) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6975573 | 0.77 | ACHE (0.67) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6976204 | 0.76 | ACHE (0.65) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6976220 | 0.75 | LMNA (0.55) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6313414 | 0.75 | LMNA (0.72) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6970981 | 0.75 | ACHE (0.75) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL6958811 | 0.75 | ACHE (0.64) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL28440118 | 0.73 | ACHE (0.85) | MAPTALDH1A1MAPK1HSD17B10LMNA | |
| Maleic Acid SCHEMBL6974397 | 0.73 | ACHE (0.61) | MAPTALDH1A1MAPK1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |