Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970961 | 0.85 | MAPT (0.53) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL1077676 | 0.78 | ADORA3 (0.48) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL1006034 | 0.77 | MAPT (0.61) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL9371698 | 0.76 | ADORA3 (0.51) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL1007416 | 0.75 | ADORA3 (0.45) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL6976448 | 0.75 | MAPT (0.54) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL6972054 | 0.74 | ALDH1A1 (0.52) | ADORA3KMT2ANPSR1MEN1LMNA | |
| SCHEMBL19993956 | 0.71 | MAPT (0.71) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL8281789 | 0.71 | LMNA (0.55) | ADORA3KMT2ANPSR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL1008231 | 0.70 | LMNA (0.54) | ADORA3KMT2ANPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120415-B1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6355663-B1 | AN ENHANCING AGENT FOR THE ACTION OF CELL DIFFERENTIATION INDUCTION FACTORS FOR BONE DISORDERS AND NERVOUS SYSTEM DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1120415-A1 | SUBSTITUTED ISOXAZOLYLTHIOPHENE COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-08-01 | — | — | EP | disclosed |