Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589724 | 0.84 | NR1H2 (0.61) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL11311344 | 0.82 | NR1H3 (0.71) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL6975297 | 0.81 | NR1H3 (0.61) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL11588467 | 0.81 | NR1H2 (0.72) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL6972656 | 0.81 | MEN1 (0.47) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL7740503 | 0.80 | NR1H2 (0.49) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL11592259 | 0.80 | NR1H2 (0.60) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL6978022 | 0.78 | NR1H2 (0.42) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL11589058 | 0.77 | NR1H2 (0.60) | NR1H2NR1H3NPC1RAB9AALDH1A1 | |
| SCHEMBL1499978 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| EP-1123287-A1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024735-A1 | INSECTICIDAL 1-(SUBSTITUTED PYRIDYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |