Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975297 | 0.84 | NR1H3 (0.61) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL7740503 | 0.83 | NR1H2 (0.49) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL6951559 | 0.81 | MEN1 (0.45) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL6967154 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3NPC1RAB9ACYP2A6 | |
| SCHEMBL6947500 | 0.80 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL1499978 | 0.79 | NR1H2 (0.46) | NR1H2NR1H3NPC1RAB9ACYP2A6 | |
| SCHEMBL7742632 | 0.78 | SIGMAR1 (0.46) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL24409819 | 0.77 | MEN1 (0.55) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL6951032 | 0.76 | MEN1 (0.43) | MEN1KMT2ANR1H2NR1H3NPC1 | |
| SCHEMBL6978022 | 0.73 | NR1H2 (0.42) | MEN1KMT2ANR1H2NR1H3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |
| EP-1123287-A1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024735-A1 | INSECTICIDAL 1-(SUBSTITUTED PYRIDYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |