Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975297 | 0.90 | NR1H3 (0.61) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL30843054 | 0.88 | NR1H2 (0.42) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL7742632 | 0.83 | SIGMAR1 (0.46) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6972656 | 0.83 | MEN1 (0.47) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL27007753 | 0.81 | NR1H2 (0.67) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6967154 | 0.80 | NR1H2 (0.47) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL1499978 | 0.76 | NR1H2 (0.46) | NR1H2NR1H3NPC1RAB9AMAPT | |
| SCHEMBL6978022 | 0.75 | NR1H2 (0.42) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6969367 | 0.73 | CYP2A6 (0.42) | NR1H2NR1H3NPC1RAB9AKDM4E | |
| SCHEMBL6975993 | 0.71 | NR1H3 (0.57) | NR1H2NR1H3NPC1RAB9AHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | claimed |