Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967154 | 0.78 | NR1H2 (0.47) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6975297 | 0.76 | NR1H3 (0.61) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL7740503 | 0.75 | NR1H2 (0.49) | NR1H2NR1H3NPC1RAB9AKDM4C | |
| SCHEMBL6972656 | 0.73 | MEN1 (0.47) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6975993 | 0.73 | NR1H3 (0.57) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL1499978 | 0.72 | NR1H2 (0.46) | NR1H2NR1H3NPC1RAB9AKDM4C | |
| SCHEMBL7742632 | 0.71 | SIGMAR1 (0.46) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL6969367 | 0.69 | CYP2A6 (0.42) | NR1H2NR1H3NPC1RAB9AKDM4E | |
| SCHEMBL11589348 | 0.62 | NR1H3 (0.54) | NR1H2NR1H3NPC1RAB9AKDM4C | |
| SCHEMBL7476369 | 0.62 | NR1H2 (0.43) | NR1H2NR1H3NPC1RAB9AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |