SCHEMBL6967510

SCHEMBL6967510

Cc1c(F)c(Oc2c(Cl)c(C(F)(F)F)nn2C)nc(-c2ccc(C(F)(F)F)cc2)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP2 O95551 1/20 0.35
GRM5 P41594 1/20 0.35
SIGMAR1 Q99720 1/20 0.33
MAPT P10636 1/20 0.33
CCR1 P32246 1/20 0.33
F10 P00742 1/20 0.32
TOP1 P11387 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DHODH Q02127 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
RAB9A P51151 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
SLC34A1 Q06495 2/20 0.32
GABRP O00591 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6722789 0.90 TDP2 (0.37) MEN1KMT2ATDP2GRM5SIGMAR1
SCHEMBL6731295 0.82 CRHR1 (0.41)
SCHEMBL6724284 0.76 ADORA2A (0.51) KMT2ATDP2GRM5SIGMAR1F10
SCHEMBL6726972 0.75 ADORA2A (0.38) KMT2ATDP2GRM5SIGMAR1F10
SCHEMBL6727231 0.73 ADORA2A (0.36) KMT2ATDP2GRM5SIGMAR1F10
SCHEMBL13066524 0.71 MEN1 (0.46) MEN1KMT2ATDP2GRM5SIGMAR1
SCHEMBL6723781 0.71 S1PR1 (0.42) F10TOP1DHODHCNR1
SCHEMBL6719360 0.70 F10 (0.61) MEN1KMT2AMAPTF10SMN1; SMN2
SCHEMBL8553190 0.69 CTSS (0.38) KCNH2MEN1KMT2ASMN1; SMN2GABRP
SCHEMBL6727226 0.68 KIF11 (0.41) TOP1DHODHKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0887343-B1 Herbicidal 3,5-difluoropyridines BASF AG (DE) 2003-06-11 EP claimed
US-6310006-B1 CONTROLLING WEEDS AMERICAN CYANAMID COMPANY 2001-10-30 US claimed
US-20010011064-A1 Herbicidal 3,5-difluoropyridines AMERICAN CYANAMID COMPANY (US) 2001-08-02 US claimed
EP-0887343-A1 Herbicidal 3,5-difluoropyridines American Cyanamid Company (US) 1998-12-30 EP claimed
EP-0887343-B1 Herbicidal 3,5-difluoropyridines BASF AG (DE) 2003-06-11 EP disclosed
US-6310006-B1 CONTROLLING WEEDS AMERICAN CYANAMID COMPANY 2001-10-30 US disclosed
US-20010011064-A1 Herbicidal 3,5-difluoropyridines AMERICAN CYANAMID COMPANY (US) 2001-08-02 US disclosed
EP-0887343-A1 Herbicidal 3,5-difluoropyridines American Cyanamid Company (US) 1998-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010011064-A1 Herbicidal 3,5-difluoropyridines DDT, CYP1B1, NQO2 KCNH2 262/4885MEN1 4524/4885KMT2A 994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.