Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398113 | 0.85 | NPC1 (0.57) | L3MBTL1TDP1MAPK1POLBALDH1A1 | |
| SCHEMBL4809726 | 0.85 | ALDH1A1 (0.60) | L3MBTL1TDP1MAPK1POLBALDH1A1 | |
| SCHEMBL20548897 | 0.83 | TSHR (0.59) | TDP1MAPK1POLBALDH1A1CES1 | |
| SCHEMBL9420685 | 0.83 | ADRB2 (0.56) | L3MBTL1TDP1MAPK1POLBALDH1A1 | |
| SCHEMBL16169034 | 0.82 | MAPK1 (0.53) | L3MBTL1TDP1MAPK1POLBALDH1A1 | |
| SCHEMBL28754539 | 0.82 | ALDH1A1 (0.53) | L3MBTL1TDP1MAPK1POLBALDH1A1 | |
| SCHEMBL9589298 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MAPK1POLBALDH1A1KMT2A | |
| SCHEMBL10730495 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MAPK1POLBALDH1A1KMT2A | |
| SCHEMBL20597997 | 0.82 | TDP1 (0.47) | TDP1MAPK1POLBALDH1A1CES1 | |
| SCHEMBL1142464 | 0.80 | CES1 (0.53) | L3MBTL1TDP1MAPK1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423211-B1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | KANEKA CORP (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2423211-A1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | Kaneka Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |