Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967604 | 1.00 | HPGD (0.37) | HPGDMAPTLMNAHTTFGF23 | |
| SCHEMBL6960418 | 0.83 | ALDH1A1 (0.35) | LMNAALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6954301 | 0.80 | — | — | |
| SCHEMBL6963970 | 0.75 | KMT2A (0.36) | ALDH1A1MEN1KMT2AMAPK1USP2 | |
| SCHEMBL8481675 | 0.68 | HPGD (0.34) | HPGDMAPTLMNAHTTFGF23 | |
| SCHEMBL6966623 | 0.66 | KMT2A (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14931402 | 0.65 | GABRA1 (0.45) | HPGDMAPTLMNAHTTFGF23 | |
| SCHEMBL14931403 | 0.65 | GABRA1 (0.45) | HPGDMAPTLMNAHTTFGF23 | |
| SCHEMBL28242379 | 0.62 | LMNA (0.43) | HPGDMAPTLMNAHTTFGF23 | |
| SCHEMBL10879139 | 0.60 | FGF23 (0.40) | HPGDMAPTLMNAHTTFGF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889033-B1 | ALPHA-SUBSTITUTED BENZYL HETEROCYCLIC DERIVATIVES, INTERMEDIATES FOR PRODUCING THE SAME, AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIONOGI & CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6329371-B1 | HERBICIDES OR FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6136837-A | α-substituted benzyl heterocyclic derivatives, intermediates for producing the same and agrochemical composition containing the same as active ingredient | SHIONOGI & CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0889033-A1 | ALPHA-SUBSTITUTED BENZYL HETEROCYCLIC DERIVATIVES, INTERMEDIATES FOR PRODUCING THE SAME, AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIONOGI & CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |