Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967641 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2TAS2R14PTGER1KDM4EALDH1A1 | |
| SCHEMBL5152406 | 0.81 | ITGA4 (0.49) | SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL6209715 | 0.79 | P2RX7 (0.43) | SMN1; SMN2PTGER1KDM4EACHEBCHE | |
| SCHEMBL6209717 | 0.79 | P2RX7 (0.43) | SMN1; SMN2PTGER1KDM4EACHEBCHE | |
| SCHEMBL6967330 | 0.79 | GAA (0.42) | SMN1; SMN2GAAATMPTGER1KDM4E | |
| SCHEMBL6209719 | 0.79 | GAA (0.38) | SMN1; SMN2GAAATMPTGER1ALDH1A1 | |
| SCHEMBL6963749 | 0.77 | MAPT (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6964802 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2GAAATMPTGER1KDM4E | |
| SCHEMBL6210163 | 0.74 | P2RX7 (0.40) | SMN1; SMN2PTGER1KDM4EALDH1A1LMNA | |
| SCHEMBL6210169 | 0.74 | P2RX7 (0.40) | SMN1; SMN2PTGER1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078249-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078249-A1 | VLA-4 inhibitor compounds | VCAM1, ICAM1, ITGA4 | SMN1; SMN2 4151/4885GAA 1709/4885ATM 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.