Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 9/20 | 0.48 |
| ▸ | GABRD | O14764 | 9/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.48 |
| ▸ | GABRE | P78334 | 9/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370302 | 0.83 | MEN1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6975980 | 0.83 | GABRB3 (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10540919 | 0.78 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6965177 | 0.76 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7963111 | 0.75 | KDR (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5826687 | 0.74 | KDR (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10371340 | 0.72 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8783671 | 0.72 | HPGD (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10389978 | 0.70 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7581732 | 0.68 | HPGD (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946515-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0946515-A1 | PARASITICIDAL PYRAZOLES | Pfizer Limited (GB) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024767-A1 | PARASITICIDAL PYRAZOLES | PFIZER LIMITED (GB) | 1998-06-11 | — | — | WO | disclosed |